Carte Computational Medicine Zlatko Trajanoski

Computational Medicine

Tools and Challenges

Limbă: engleză
Legare: Copertă tare
Disponibilitate: În depozitul extern
Expediem în 10-13 zile
992.21 lei
Computational methodologies and modeling play an increasing role for investigating mechanisms, and f...

Informații despre carte

Limbă
engleză
Legare
Carte - Copertă tare
Publicat
2012
Pagini
203
EAN
9783709109465
ISBN
3709109469
Enbook ID
01705710
Greutate
621
Dimensiuni
178 x 254 x 17

Descriere completă

Computational methodologies and modeling play an increasing role for investigating mechanisms, and for diagnosis and therapy of human diseases. This progress gave rice to computational medicine, an interdisciplinary field at the interface of computer science and medicine. The main focus of computational medicine lies in the development of data analysis methods and mathematical modeling and computational simulation techniques specifically addressing medical problems. In this book we present a number of computational medicine topics spanning several scales: from molecular to cell to organ and organism. First, state-of-the-art IT infrastructure for biomedical research is presented. Then four hierarchical scales are shown: 1) At the molecular level tools are reviewed for the analysis of genome variations, gene expression data, protein sequence data, proteomics, metabolomics, and 3D structural data; 2) At the cellular level approaches in oncology and artherosclerosis are highlighted; 3) At the organ level computational anatomy tools are described; and 4) at the organism level multi-scale modeling approach with special focus on oncology is presented.Computational methodologies and modeling play an increasing role for investigating mechanisms, and for diagnosis and therapy of human diseases. This progress gave rice to computational medicine, an interdisciplinary field at the interface of computer science and medicine. The main focus of computational medicine lies in the development of data analysis methods and mathematical modeling and computational simulation techniques specifically addressing medical problems. In this book we present a number of computational medicine topics spanning several scales: from molecular to cell to organ and organism. First, state-of-the-art IT infrastructure for biomedical research is presented. Then four hierarchical scales are shown: 1) At the molecular level tools are reviewed for the analysis of genome variations, gene expression data, protein sequence data, proteomics, metabolomics, and 3D structural data; 2) At the cellular level approaches in oncology and artherosclerosis are highlighted; 3) At the organ level computational anatomy tools are described; and 4) at the organism level multi-scale modeling approach with special focus on oncology is presented.

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