Carte Coated Implant Surfaces Petra M. Dorfner

Coated Implant Surfaces

Influence of RGD Coating in Combination with Surface Properties on the Adhesion Process of Osteoblasts

Limbă: engleză
Legare: Carte broșată
Disponibilitate: În depozitul extern
Expediem în 8-11 zile
335.05 lei
A profound knowledge of bony in growth is the basis for the development of biofunctionalized implant...

Informații despre carte

Limbă
engleză
Legare
Carte - Carte broșată
Publicat
2012
Pagini
140
EAN
9783838135106
ISBN
3838135105
Enbook ID
06920641
Greutate
213
Dimensiuni
152 x 229 x 8

Descriere completă

A profound knowledge of bony in growth is the basis for the development of biofunctionalized implants. The positive influence of RGD peptides and surface properties of implant material on cell adhesion is well known. With the aim to reveal potential synergies, we functionalized different Ti6Al4V disks with highly active v-specific RGD peptides. Our integrin binding studies yielded the most promising results for the combination of peptide coating and rough surfaces. Cell adhesion experiments performed with characterized human primary osteoblasts demonstrated that cells adhere more strongly on rough surfaces coated with peptide compared to smooth ones. We showed that peptide coating and surface topography influence the adhesion kinetics particularly at the early stage. Cell spreading was accelerated on Ti6Al4V disks immobilized with peptides within the first hour, while after longer incubation times this effect is less pronounced. The combination of RGD peptide coating with optimized topological surface properties of implant materials bears the potential to increase osseointegration.

S-ar putea să te intereseze

Salt Houses

Hala Alyan
52.91 lei

President without a Party

Christopher J. Leahy
184.05 lei
701.55 lei

Surfer Dude

Miss Heather
52.71 lei

On Augustine

Alan Ryan
79.12 lei
128.91 lei

Luke for All Seasons

Douglas T Stave Ed D
89.40 lei

Clienții care au cumpărat această carte au mai cumpărat și