Carte Circadian Pharmacokinetics Danyi Lu

Circadian Pharmacokinetics

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This book summarizes the recent advances for the understanding of circadian clock system in the regu...

Informații despre carte

Limbă
engleză
Legare
Carte - Carte broșată
Publicat
2021
Pagini
253
EAN
9789811588099
ISBN
9811588090
Enbook ID
37371184
Greutate
409
Dimensiuni
155 x 235 x 15

Descriere completă

This book summarizes the recent advances for the understanding of circadian clock system in the regulation of drug metabolism and pharmacokinetics. Basic knowledge in the field of circadian clock and pharmacokinetics are systemically introduced to make it easier for readers to understand the entire book's contents. The rhythmic expression of DMEs (drug-metabolizing enzymes) and transporters are summarized, and the underlying mechanisms thereof (i.e., regulation by circadian oscillators) are discussed. Typically, evidence for the DME- and transporter-mediated chronopharmacokinetics, chronotoxicity and chronoefficacy are highlighted in this book.

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