Chemokines

Name: Chemokines
Brand: Humana Press Inc.
SKU: 9781627034258
Price: 810.46 RON
Availability: InStock

Methods and Protocols

Autor: Astrid E. Cardona, Eroboghene E. Ubogu

Limbă:

Legare: Copertă tare

Editura: Humana Press Inc.

Disponibilitate: În depozitul extern

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Chemokines constitute a large family of structurally similar cytokines that contain a signature of c...

Informații despre carte

Autor

Astrid E. Cardona, Eroboghene E. Ubogu

Limbă

engleză

Legare

Carte - Copertă tare

Publicat

2013

Pagini

238

EAN

9781627034258

ISBN

1627034250

Enbook ID

01433052

Editura

Humana Press Inc.

Greutate

6221

Dimensiuni

178 x 254 x 20

Descriere completă

Chemokines constitute a large family of structurally similar cytokines that contain a signature of conserved cysteine residues joined by disulfide bridges. Binding of chemokines to specific G protein-coupled receptors followed by downstream signaling defines their biological function. Initially, chemoattraction was the key function linked to chemokines/chemokine receptors; however, in recent years, it has become clear that chemokine ligand-receptor interactions can also modulate cellular activation, survival, and proliferation, among other functions in homeostatic and diseased states. Importantly, major advances in our understanding of chemokine biology have led to chemokine receptors becoming specific therapeutic targets with great potential. In Chemokines: Methods and Protocols, expert researchers provide practical information regarding experimental models and state of the art protocols used to delineate chemokine/chemokine receptor function and their applications in health and disease. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. §Practical and easy to use, Chemokines: Methods and Protocols aims to reveal key protocols of functional and descriptive chemokine ligand/receptor assays that will be of practical significance to graduate students, post-doctoral fellows, trainees, and researchers in academia and industry.

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Chemokines

Methods and Protocols

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