Chemical Mutagens

Name: Chemical Mutagens
Brand: Springer-Verlag New York Inc.
SKU: 9781461336969
Price: 276.36 RON
Availability: InStock

Principles and Methods for Their Detection Volume 8

Autor: Frederick J. De Serr, A. Hollaender

Limbă:

Legare: Carte broșată

Editura: Springer-Verlag New York Inc.

Disponibilitate: În depozitul extern

Expediem în 5-8 zile

276.36 lei

Volume 8 of Chemical Mutagens covers a wide range of topics in this continuously changing field. Thi...

Informații despre carte

Autor

Frederick J. De Serr, A. Hollaender

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2011

Pagini

386

EAN

9781461336969

ISBN

1461336961

Enbook ID

02180304

Editura

Springer-Verlag New York Inc.

Greutate

589

Dimensiuni

152 x 229 x 22

Descriere completă

Volume 8 of Chemical Mutagens covers a wide range of topics in this continuously changing field. This volume includes chapters on the detection of genetic damage in mammalian sperm both at specific loci and over the entire genome. The discussion of in vitro techniques for working with mammalian cells covers not only specific locus assays but also cellular activation systems. Another chapter extensively discusses the need for a revised protocol for the micronucleus assay. Structure activity relationships are investigated in a chapter dealing with hair dye constituents. One of the most comprehensive chapters deals with problems associated with the detection of mutagenic effects in defined human populations. Finally, there is a detailed presentation of a comprehensive study tabulating the genetic bioassay data on some known or suspected human carcinogens. In keeping with our policy of publishing important legislation in the area of chemical mutagens, we have also included the Council of the European Communities Directive of 18 September 1979. Frederick J. de Serres Research Triangle Park, North Carolina vii Contents Chapter 1 Detection of Effects of Mutagens in Human Populations George R. Hoffmann 1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 2. Monitoring Progeny for Evidence of Germ-Cell Mutations. . . . . 3 2. 1. The Classical Approach: Phenotypic Monitoring . . . . . . . 3 2. 2. Monitoring for Changes in Gene Products . . . . . . . . . . . 7 3. Detection of Gene Mutations in Somatic Cells. . . . . . . . . . . . . 9 3. 1. Drug-Resistant Lymphocytes . . . . . . . . . . . . . . . . . . . . . . 9 3. 2. Hemoglobin Variants . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 4. Nongenetic Indicators of Mutagen Exposure . . . . . . . . . . . . . 21 4. 1. Alkylation of Proteins . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 4. 2. DNA Damage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

S-ar putea să te intereseze

Clienții care au cumpărat această carte au mai cumpărat și

Cele mai căutate

Categories

Authors

Publishers

Produse

Produse

Cele mai căutate

Categories

Authors

Publishers

Produse

Produse

Chemical Mutagens

Principles and Methods for Their Detection Volume 8

Informații despre carte

Descriere completă

S-ar putea să te intereseze

Clienții care au cumpărat această carte au mai cumpărat și