Cell Polarity and Subcellular RNA Localization

Name: Cell Polarity and Subcellular RNA Localization
Brand: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
SKU: 9783642074363
Price: 1100.99 RON
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Autor: Dietmar Richter

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Editura: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

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Selective cytoplasmic organelle and protein targeting has long been thought to constitute the sole d...

Informații despre carte

Autor

Dietmar Richter

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2010

Pagini

221

EAN

9783642074363

ISBN

3642074367

Enbook ID

01652578

Editura

Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

Greutate

406

Dimensiuni

155 x 235 x 13

Descriere completă

Selective cytoplasmic organelle and protein targeting has long been thought to constitute the sole determinant of cell polarity and complexity. This view has been changed, however, by the discovery of differential subcellular RNA distribution patterns. Over the past decade it has become clear that selective mRNA sorting and translation contributes to an accumulation of cognate proteins at discrete cellular sites. In this book, various systems are discussed (e.g. Xenopus oocytes, mammalian brain, invertebrate nervous system) in terms of RNA trafficking, RNA-targeting sequences (cis-elements) and RNA-transporting proteins (trans-factors), activity-dependent translational regulation and the significance of the cytoskeleton for neuronal function and plasticity. It also discusses nucleocytoplasmic export of mRNA and viral RNA as another example of subcellular RNA kinesis.

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Cell Polarity and Subcellular RNA Localization

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