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Carte Cell Fusions Lars-Inge Larsson

Cell Fusions

Regulation and Control

Autor: Lars-Inge Larsson
Limbă: engleză
Legare: Copertă tare
Editura: Springer
Disponibilitate: În depozitul extern în cantități mici
Expediem în 11-15 zile
1 152.41 lei
Cell fusions are important to fertilization, placentation, development of skeletal muscle and bone,...

Informații despre carte

Autor
Lars-Inge Larsson
Limbă
engleză
Legare
Carte - Copertă tare
Publicat
2010
Pagini
436
EAN
9789048197712
ISBN
9048197716
Enbook ID
01976951
Editura
Springer
Greutate
780
Dimensiuni
172 x 242 x 23

Descriere completă

Cell fusions are important to fertilization, placentation, development of skeletal muscle and bone, calcium homeostasis and the immune defence system. Additionally, cell fusions participate in tissue repair and may be important to cancer development and progression. A large number of factors appear to regulate cell fusions, including receptors and ligands, membrane domain organizing proteins, proteases, signaling molecules and fusogenic proteins forming alpha-helical bundles that bring membranes close together.§The purpose of the planned volume is to sum up current knowledge about mechanisms regulating and controlling cell fusions. The field has expanded vastly within the past few years and leaders in the field will be invited to contribute with current overviews of their specific areas of knowledge. Attention will be paid both to true fusogens like proteins encoded by the viral (e.g. HIV), caenorhabdidtis (EFF) mammalian and human (e.g. syncytins and Pb-1) genomes as well as to mechanisms regulating the activities of the fusogens. The commitment of cells to fuse represents an irreversible step. It stands to reason that a number of factors controlling and safe-guarding these mechanisms must exist. It seems equally reasonable to assume that many of these mechanisms are redundant in different systems. By bringing together experts working in each their system there is a fair chance that a consensus concerning the mechanistics of cell fusions may develop.

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