Cell adhesion behavior on molecularly engineered surfaces

Name: Cell adhesion behavior on molecularly engineered surfaces
Brand: LAP Lambert Academic Publishing
SKU: 9783659190391
Price: 405.68 RON
Availability: InStock

Mechanisms of Cell/Surface Interaction

Autor: Ning Cai

Limbă:

Legare: Carte broșată

Editura: LAP Lambert Academic Publishing

Disponibilitate: La editor doar la comandă

Expediem în 17-27 zile

405.68 lei

Effective attachment of cells on biomaterials is one important requirement in designing engineered t...

Informații despre carte

Autor

Ning Cai

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2012

Pagini

220

EAN

9783659190391

Enbook ID

06901451

Editura

LAP Lambert Academic Publishing

Greutate

308

Dimensiuni

150 x 220 x 11

Descriere completă

Effective attachment of cells on biomaterials is one important requirement in designing engineered tissue substitute. Better understanding of biophysical responses of adherent cells is of great importance in optimizing biomaterial surface for tissue engineering applications. In this work, poly(lactic acid) (PLA) and carbon nanotubes (CNT), were surface-modified with extracellular matrix (ECM) proteins to improve their compatibility. The results of adhesion dynamics of porcine esophageal fibroblasts (PEFs) on ECM protein-immobilized PLA and CNT monolayer demonstrate the different biophysical responses of PEFs on unmodified and ECM protein-modified biomaterial surfaces. ECM protein immobilization effectively promotes adhesion of PEFs to biomaterials surfaces. In addition, it is found that functional blocking of 1 integrin impaires cell-fibronectin interactions. Adhesion strength is tightly correlated to focal adhesion density, which is explained by peeling and fracture models. Furthermore, Weibull distribution is proved to satisfactorily describe cell adhesion strength in adherent cell population.

S-ar putea să te intereseze

Clienții care au cumpărat această carte au mai cumpărat și

Cele mai căutate

Categories

Authors

Publishers

Produse

Produse

Cele mai căutate

Categories

Authors

Publishers

Produse

Produse

Cell adhesion behavior on molecularly engineered surfaces

Mechanisms of Cell/Surface Interaction

Informații despre carte

Descriere completă

S-ar putea să te intereseze

Clienții care au cumpărat această carte au mai cumpărat și