engleză
This book is devoted entirely to the chemical synthesis of carotenoids.§The main text consists of four sections, each dealing with a major theme. The essential in-depth appreciation of the perspectives, principles and strategies of carotenoid synthesis is provided in the first chapter. Preparation of polyene synthons and carotenoid end groups, and the coupling reactions commonly used for carbon-carbon double bond formation, as well as the application of these methods and synthons for the synthesis of carotenoids, are then described in detail.§The commercially important technical syntheses used for large scale industrial production of carotenoids, and methods for the preparation of isotopically labelled carotenoids, in particular for biological and medical applications, are also covered.§Examples describe in detail reliable and efficient procedures for key reactions. Tables of useful synthons and a list of natural carotenoids prepared by total synthesis are included as appendices.
