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This volume provides the reader with the most up-to-date results of both fundamental and clinical studies covering a broad area of brain tumor research. It comprises 46 papers specially selected from among the 13 special lectures and 145 presentations delivered at the 3rd Japanese Conference on Brain Tumor Research and Therapy held in Nasu, 1994, and is divided into four parts: 1. a reevaluation of brain tumor classification and grading, 2. the dynamic aspects of brain tumor cells, 3. molecular neurooncology and its impact on clinical management, and 4. advances in novel therapeutic approaches, including biological response markers (BRM) and gene therapy. Both research and treatment of brain tumors in Japan are among the best in the world. This monograph includes the latest findings from Japan, the US, and Europe and represents an extremely valuable source of reference for researchers internationally. Fundamental researchers will be able to discern the direction of neurooncological studies on brain tumors, and neurosurgeons and clinical oncologists will be able to develop their therapeutic approaches based on the reported results in this volume.
