Carte Bioreactor Processes Based on Disposable Materials Matthieu Stettler

Bioreactor Processes Based on Disposable Materials

for the production or recombinant proteins from mammalian cells

Limbă: engleză
Legare: Carte broșată
Editura: VDM Verlag
Disponibilitate: În depozitul extern
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328.35 lei
The objective of industrial cell culture technology is to produce high value-added therapeutic prote...

Informații despre carte

Limbă
engleză
Legare
Carte - Carte broșată
Publicat
2009
Pagini
152
EAN
9783639150285
ISBN
3639150287
Enbook ID
06823570
Editura
Greutate
242
Dimensiuni
151 x 229 x 9

Descriere completă

The objective of industrial cell culture technology is to produce high value-added therapeutic proteins that are well suited for the treatment of infectious diseases, cancer, and autoimmune diseases. Nowadays, an important focus is the reduction of the time and costs from the discovery of the candidate molecule to the full-scale production. Relying on enabling technologies is critical for meeting this objective. Simultaneously, novel technologies are expected to increase the clinical and commercial success rates. In recent years, new concepts based on innovative disposable materials emerged and appeared to be promising alternatives to standard bioprocessing equipment. This thesis work focused on the development of such disposable compounds in mammalian cell culture applications, particularly for the containment of the cells, and was aimed at demonstrating their benefit in terms of cost- effectiveness, ease-of-use and flexibility. Most importantly, it established that orbital shake technology can be used for a wide range of operating scales, from only a few milliliters for optimization purposes up to production scale.

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