Biopharmaceuticals

Name: Biopharmaceuticals
Brand: VDM Verlag
SKU: 9783639136067
Price: 436.69 RON
Availability: InStock

A Study of Apoptosis and Cell Cycle to Augment Transfection Efficiency in Chinese hamster ovary (CHO) Cells

Autor: Nico Wanandy

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Legare: Carte broșată

Editura: VDM Verlag

Disponibilitate: În depozitul extern

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436.69 lei

In the biopharmaceutical industry, essentially, there§are three components that play the main role i...

Informații despre carte

Autor

Nico Wanandy

Limbă

engleză

Legare

Carte - Carte broșată

Publicat

2009

Pagini

264

EAN

9783639136067

ISBN

3639136063

Enbook ID

06822284

Editura

VDM Verlag

Greutate

390

Dimensiuni

152 x 229 x 15

Descriere completă

In the biopharmaceutical industry, essentially, there§are three components that play the main role in§producing biopharmaceutical products, the host cell,§the expression vector and the bioreactor and/or§production environment. To produce the highly valued§and desired products, the choice of a suitable host§is one of the most important aspects. The host§required is not only required to produce the desired§product, but also needs to demonstrate robustness in§a bioreactor system. Constantly facing challenges in§a bioreactor, cells often undergo apoptosis, a§well-known limiting factor in biopharmaceutical§production, which ultimately leads to low yield of§valuable protein(s). We have genetically engineered§a CHO-K1 cell line to constitutively express human§insulin-like growth factor-1 (IGF-1) and murine§polyoma large T-antigen (PyLT-Ag) to generate§Super-CHO and CHO-T respectively, two cell lines that§can potentially serve different niches in the§biopharmaceutical industry.

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Biopharmaceuticals

A Study of Apoptosis and Cell Cycle to Augment Transfection Efficiency in Chinese hamster ovary (CHO) Cells

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