Biodegradable Long Acting Injectables and Implants

Name: Biodegradable Long Acting Injectables and Implants
Brand: Springer, Berlin
SKU: 9783031723018
Price: 989.21 RON
Availability: InStock

An Industry View

Autor: Farshad Ramazani

Limbă:

Legare: Copertă tare

Editura: Springer, Berlin

Disponibilitate: În depozitul extern

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Long acting injectables and implants (LAI) are known to improve patient adherence and treatment outc...

Informații despre carte

Autor

Farshad Ramazani

Limbă

engleză

Legare

Carte - Copertă tare

Publicat

2025

Pagini

200

EAN

9783031723018

Enbook ID

46582554

Editura

Springer, Berlin

Greutate

514

Dimensiuni

155 x 235

Descriere completă

Long acting injectables and implants (LAI) are known to improve patient adherence and treatment outcomes. They reduce costs for the healthcare system and ensure sustainable sales for pharmaceutical companies. LAI are usually administered intramuscularly (IM) or subcutaneously (SC). In this way, the drug is released from its depot in a controlled manner over a longer period of time (e.g., a few days to a year). There is a trend toward increasing interest in the development of long-acting drugs for local administration versus systemic administration of depot products (i.e., IM or SC injection). This is leading to finding new ways of administration of the depot formulation, intra-ocular, intra-articular, pri-tendon etc. Therefore, it is expected that more drugs based on LAI formulations will enter the clinical phase in the future. Due to many benefits in adherence, efficacy, and safety of the treatment up until now around 50 brand name medicines using different biodegradable long-acting technology have received FDA approval. Manufacturing of LAI involves many steps with their unique challenges, which is why pharmaceutical companies consider them to be complex formulations to develop. Most of the published papers and books in this field are written by scientists who never worked in industry and whose knowledge on the topic is limited to small scale formulation screening. Therefore, this book aims to address the challenges of the development of biodegradable LAI from an industrial perspective.

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Biodegradable Long Acting Injectables and Implants

An Industry View

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Descriere completă

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